Assistant Professor, Simons Center for Quantitative Biology

B.S., Heidelberg University, Germany

M.Sc., Heidelberg University, Germany

Ph.D., Cambridge University, United Kingdom

The immune system exists in an intricate balance. Inappropriate response to the body’s own antigens leads to autoimmunity, but a lack of appropriate response to foreign invaders results in immunodeficiency. The thymus plays a key role in establishing this balance by presenting the body’s self-antigens to developing T cells in a process called central tolerance induction. The overarching objective of the Meyer lab research program is to understand T-cell tolerance induction in the human thymus and its functional consequences. Thus far, insights into human thymus function have been mostly descriptive. The Meyer lab seeks to significantly extend this understanding by conducting mechanistic and functional studies of human thymus physiology, leveraging in silico and statistical models, genomics, and advanced imaging technologies.