Neil Dani
Assistant Professor, Cell and Developmental Biology
B.S., University of Rochester
M.S., New York Medical College
Ph.D., Vanderbilt University
The Dani lab researches the choroid plexus, a fascinating and understudied structure in the brain that generates cerebrospinal fluid and nourishing substances that support brain health throughout life. Recently with collaborators, we generated detailed maps of the choroid plexus, which reveal the cellular sources of the nourishing substances and several additional cell types, suggesting previously unappreciated functions. We believe that the breakdown of these cellular functions contributes to neurological and neurogenerative disorders such as Alzheimer’s disease, and that further research could provide novel insights into potential new prevention methods or treatments. To investigate, we are using cutting edge imaging tools that enable us to directly visualize the activity of choroid plexus cells in real time.