William Renthal

Associate Professor, Neurology; and Director, Headache Research

Ph.D., University of Texas Southwestern Medical Center

M.D., University of Texas Southwestern Medical Center

In conjunction with Margaret and William R. Hearst III

The Renthal lab studies the genomic and epigenomic mechanisms that contribute to conditions related to refractory headache and facial pain. This work aims to reveal molecular features that are unique to pain-related cells and circuits that could be used to develop novel strategies for pain therapeutics with fewer side effects. Dr. Renthal also co-directs the Harvard PRECISION Pain Center, an NIH-funded network of pain clinicians and scientists who are leveraging advanced multi-omic technologies to characterize the specific cell types and states associated with pain using human samples. Together, this work aims to improve translation of basic research discoveries into safer treatments for patients with refractory headache and/or pain conditions.